"ignorance more frequently begets confidence than does knowledge"
Charles Darwin, The Descent of Man, 1871.
"There can be no possible quarrel with science that ignorance can improve."
George Wald, 1970 Massey Lectures, Part 1.
As the most refined aid to understanding so far developed by mankind, science owes the greater part of its advance over other paths of knowledge to its subordination of the human intellect to the verdict of evidence. Thus, to do science means to be prepared to be wrong.
"If you really care about having your beliefs correspond to reality, you have to be prepared to face, and act on, the possibility that they don’t."
Geoffrey D. Falk